Description
What is Trifluoromethanesulfonyl chloride？
Trifluoromethanesulfonyl chloride is a chemical substance with the chemical formula CF₃SO₂Cl, a molecular weight of 168.52. It appears as a colorless to pale yellow liquid with a boiling point of 30.5 ± 0.0 °C, a melting point of -26 °C, a density of 1.8 ± 0.1 g/cm³, a vapor pressure of 624.2 ± 0.0 mmHg (25 °C), a flash point of -32.0 ± 25.9 °C, and a refractive index of 1.359. Storage conditions: Sealed under argon gas and stored in a dry environment at 4°C.
What are applications of Trifluoromethanesulfonyl chloride?
Trifluoromethanesulfonyl chloride is a reagent widely used for the direct trifluoromethylation of various substrates and serves as a trifluoromethylating agent for aromatic compounds and alkenes catalyzed by ruthenium(II) complexes. It is also used in direct trifluoromethylsulfonylation and trifluoromethylsulfonation reactions to introduce SCF₃ and S(O)CF₃ groups, respectively. In addition, this reagent can be used in other reactions such as sulfonation and chlorination.
