Description
Product Name: Iodomethane-¹³C | ¹³CH₃I
CAS: 4227-95-6
Purity: ≥99.0%
Enrichment: 97.5 atom % ¹³C ~ 99 atom % ¹³C
Product specifications: 1 g, 5 g, 10 g, 25 g, 100 g
Main use: Pharmaceutical R&D, Organic Research, and Analytical Testing.
Availability: In Stock
What is Iodomethane-¹³C (¹³CH₃I)?
Iodomethane-¹³C (¹³CH₃I) is a molecule of iodomethane (methyl iodide) in which the carbon atom of the methyl group is the carbon-13 isotope (¹³C) rather than the more common carbon-12 (¹²C). It is a colorless, volatile liquid that is highly toxic, light-sensitive, and typically stabilized with copper wire to prevent decomposition during storage and use. Its molecular weight is approximately 142.93 g/mol (ordinary ¹²CH₃I: ~141.94 g/mol). This small mass difference, together with the NMR-active nature of the ¹³C nucleus (spin I = 1/2), makes ¹³CH₃I an exceptionally powerful non-radioactive stable isotope tracer and a standard reference material for tracking carbon atoms through complex chemical and biological systems.
Certificate of Analysis
| Component | Unit | Specification |
|---|---|---|
| CH₃I Chemical Purity | % | ≥99.0 |
| ¹³C | atom % | 97.5 ~ 99 |
China Isotope Development Co.,Ltd is professional in supplying stable isotope products (such as Iodomethane-¹³C) to the market over the past years as per client’s particular packages. We are a qualified supplier of many hospitals and researchers, gaining their trust ranging from quality, price, to delivery. We know each parameter of the product, to solve their questions on site, and pursue to continue serving clients better.
To conduct our commitment of being a reliable partner to offer solutions when you need specialty gases & Chemicals. Visit us at www.asiaisotopeintl.com.
What are applications of Iodomethane-¹³C (¹³CH₃I)?
Iodomethane-¹³C (¹³CH₃I) is a highly versatile stable isotope tracer and a classic methylating agent. Because the ¹³C isotope is non-radioactive and can be easily detected by advanced instruments, it serves as a critical building block across pharmaceutical, scientific, and analytical fields.
1. Pharmaceutical R&D
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Core Methylating Agent: It is used as a primary reagent for introducing a ¹³C-labeled methyl group (-¹³CH₃) into drug molecules and pharmaceutical intermediates.
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Intermediates & Standards: Essential for preparing various labeled pharmaceutical intermediates and drug metabolite standards.
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Supporting Critical Studies: These labeled compounds support crucial research such as pharmacokinetics (PK) and drug metabolism (DMPK). Researchers can accurately track how a drug is absorbed, distributed, metabolized, and excreted in the body.
2. Organic & Life Sciences Research
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Fundamental Methylation Building Block: As a classic SN2 methylating reagent, it is widely applied in organic synthesis to attach a labeled methyl group to nucleophiles.
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Reaction Mechanisms: Chemists use it to investigate organic reaction mechanisms, tracking exactly where a methyl group attaches during a chemical transformation.
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Protein NMR & Structural Biology: It enables the introduction of ¹³C-labeled methyl groups into proteins for structural and dynamic analysis by ¹³C-NMR.
3. Analytical Testing & Quality Control
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Internal Standards & Calibration: Widely used to formulate isotope internal standard reagents and calibration standard solutions.
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Precision Analysis: Highly compatible with various precision analytical scenarios, such as Mass Spectrometry (MS) and Chromatography (GC/LC). Using ¹³CH₃I as an internal standard helps eliminate matrix effects and instrument fluctuations, ensuring highly accurate and reliable quantitative results.
Why Choose Our Iodomethane-¹³C (¹³CH₃I)?
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High Purity & Stability: Consistent high isotopic purity grades (≥99 atom % ¹³C) and high chemical purity (≥99.0%), supplied with copper wire stabilizer to protect your tracer studies, synthetic reactions, and analytical processes from decomposition or contamination-related failures.
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Reliable & Stable Supply: We offer better supply security and scalability compared to traders and middlemen who depend on others for stock.
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Lower Total Cost of Ownership: Direct supply = competitive price + fewer rejections + less downtime + higher yield. You save money where it matters most—not just on the product price.
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Full Traceability & Compliance: Complete production traceability and international certifications that meet the demanding requirements of research and biomedical industries.
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Technical Expertise: In-depth manufacturer expertise to support your specific application—not just selling chemicals, but helping you use it optimally and safely.
Packaging & Delivery Options
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Standard Package: 1 g, 5 g, 10 g, 25 g, 100 g .
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Customized packages available.
Frequently Asked Questions (FAQs)
Q1. What is Iodomethane-¹³C (¹³CH₃I) ?
A: It is a special type of liquid chemical used in laboratories. The carbon inside it is a natural, slightly different kind of carbon (Carbon-13) that can be easily detected by special machines. This makes it very useful for tracking.
Q2. What is it mainly used for?
A: It is used in medical research, industrial testing, and general scientific studies. Researchers use it to attach a “tracking tag” to molecules so they can follow how carbon moves and changes in different processes.
Q3. Is it natural or radioactive?
A: It is completely natural and not radioactive at all. Carbon-13 is naturally found in all living things and everyday materials. We simply concentrate it to make this product.
Q4. How should it be stored?
A: It must be kept in a securely sealed glass bottle. You should store it in a refrigerator (2–8 °C), away from light, heat, and sunlight. The copper wire inside helps keep it stable.
Q5. Is it safe to handle?
A: No, it must be handled with great care. It is highly toxic if swallowed, inhaled, or in contact with skin, and it may cause cancer. It must only be used by trained professionals in a well-ventilated area (like a fume hood) with full protective equipment.
Q6. Is it bad for the environment?
A: Yes, it is toxic to aquatic life. It should be handled carefully to avoid unnecessary spills, and it must be disposed of according to local chemical waste regulations.
Q7. Are there special rules for shipping it?
A: Yes. Because it is a highly toxic liquid, it is classified as a hazardous material (UN 2644, Class 6.1, Packing Group I). It must be transported safely in approved containers by trained professionals. Air transport is generally restricted.
Q8. Why is it useful for research?
A: It acts like a tiny “tracking tag.” Because special machines can easily see it, scientists can follow exactly where the carbon goes during tests without disturbing the process.
Q9. Why choose this instead of regular iodomethane?
A: You only choose this if you need to track the carbon. It is not safer than regular iodomethane—it is just easier for machines to detect. If you don’t need to track it, regular iodomethane is enough.
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